Balfour Beatty is responsible for the construction of the extension wind project, which features 54 turbines to generate 162MW of power.
Clyde Extension community liaison manager Kirstanne Land said: "With construction starting at Clyde extension wind farm, we are keen to continue an open dialogue with local people to manage any potential impact and disruption carefully.
"Throughout construction and operation, the Clyde extension project is expected to bring significant local benefits to the South Lanarkshire, Scottish Borders and Dumfries and Galloway regions through direct and in-direct employment, skills training and over £20m of long-term support for community projects from the community benefit fund."
Planned to be completed in two years, the construction of the project is expected to contribute about £121m to the Scottish economy.
A community council liaison group, which has been established by SSE and includes representatives from each community council, will meet during the construction period to discuss potential issues related to the local communities.
Approved by the Scottish Government in July last year, the extension project is likely to create an infill between the central and north sections of the existing Clyde wind farm.
Completed in 2011, the existing Clyde wind farm features 152 turbines.
