The wind farm, which is expected to support over 750 jobs and bring over £2bn of investment into the UK’s economy, will feature up to 175 turbines to be installed about 13km to 20km away from the coast.
Onshore construction is due to commence in 2015, with the project planned to be completed in phases over the next four years.
Upon completion, the facility would generate enough electricity to power approximately 450,000 homes.
UK Energy and Climate Change Secretary Ed Davey said, "We’re driving investment in our energy security, and our plans have made us number one in the world for investment in offshore wind energy."
"This project is great news for Sussex, providing green jobs as well as driving business opportunities right across the country in a sector with a clear roadmap for long-term growth."
E.ON Renewables chief operating officer Michael Lewis said: "This is a key milestone for the project and we firmly believe Rampion will play an important role in helping to ensure future security of supply and make a significant contribution towards meeting the UK’s renewable energy targets."
